BETHESDA, Md., Jan 22, 2008 (UPI via COMTEX) -- U.S. scientists have identified
four genes that interact with serious obstetric complications to increase the
risk for schizophrenia.
National Institute of Mental Health researchers in Bethesda, Md., examined 13
genes believed to play a role in the development of schizophrenia. All of the
genes also play a role in supplying blood to the brain, or are influenced by
hypoxia -- a condition in which insufficient oxygen is present for proper
cellular functioning.
A subset of individuals tested had experienced at least one serious obstetric
complication, many having the potential to lead to hypoxia.
The researchers determined individuals who had four specific genetic variations,
and who also had experienced at least one serious obstetric complication, were
significantly more likely to develop schizophrenia as adults.
The study appears in the online issue of the journal Molecular Psychiatry.
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Copyright 2008 by United Press International